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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| VARDENAFIL
| VARDENAFIL | GENITO | ORAL | Cmax 36.8 NANOMOLAR Tmax 1 HOUR F 15 PERCENT VD 208 LITER PPB 95 PERCENT Cl 56 LITER / HOUR HT 4.5 HOUR | PHOSPHODIESTERASE 5 | PHOSPHODIESTERASE 5A INHIBITOR CHEMBL1827 PHOSPHODIESTERASE 5A O76074 CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE HOMO SAPIENS ENZYME PHOSPHODIESTERASE PDE_5 PDE_5A | EMA | |||
