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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TELITHROMYCIN DISCONTINUED
| TELITHROMYCIN | ANTIINFECTIVES | ORAL | Cmax 2.46 MICROMOLAR Tmax 1 HOUR F 57 PERCENT VD 188 LITER PPB 65 PERCENT Cl 54.6 LITER / HOUR (65 KILOGRAM) HT 10 HOUR | 50S RIBOSOMAL SUBUNIT PDB 4V7Z (STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH TELITHROMYCIN.) LIGAND CODE = TEL (link to the list of PDB complexes) Download experimental 3D coordinates of TEL with added hydrogens | BACTERIAL 70S RIBOSOME INHIBITOR CHEMBL2363135 BACTERIAL 70S RIBOSOME 23S RIBOSOMAL RNA BACTERIA | EMA | |||
