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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DROSPIRENONE
| DROSPIRENONE |
GENITO | ORAL | Cmax 239.6 NANOMOLAR Tmax 1.7 HOUR F 76 PERCENT VD 260 LITER (65 KILOGRAM) PPB 97 PERCENT Cl 5.8 LITER / HOUR (EQN) HT 30.9 HOUR | PROGESTERONE RECEPTOR | PROGESTERONE RECEPTOR AGONIST CHEMBL208 PROGESTERONE RECEPTOR P06401 PROGESTERONE RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3C NR3C3 | EMA | |||
