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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| OXYCODONE
| OXYCODONE |
NERVOUS SYSTEM | ORAL | Cmax 312.7 NANOMOLAR Tmax 2.1 HOUR F 73.5 PERCENT VD 169 LITER (65 KILOGRAM) PPB 45 PERCENT Cl 48 LITER / HOUR HT 4.5 HOUR SOLUBILITY IN WATER 1 GRAM / 6 MILLILITER | OPIOID RECEPTOR | MU OPIOID RECEPTOR AGONIST CHEMBL233 MU OPIOID RECEPTOR P35372 MU-TYPE OPIOID RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE OPIOID RECEPTOR | EMA | |||
