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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CORTISONE ACETATE (has an active metabolite)

CORTISONE ACETATE


ATC H02AB10
ATC S01BA03

METABOLISM
GLUCOCORTICOID
ANTIINFLAMMATORY
VASOCONSTRICTOR
REPLACEMENT THERAPY IN ADRENOCORTICAL DEFICIENCY STATES
PSORIATIC
ARTHRITIS RHEUMATOID ARTHRITIS
RAPIDLY HYDROLYZED IN CORTISONE

INJECTION ORAL

SOLUBILITY INSOLUBLE IN WATER

GLUCOCORTICOID RECEPTOR

GLUCOCORTICOID RECEPTOR AGONIST CHEMBL2034 GLUCOCORTICOID RECEPTOR P04150 GLUCOCORTICOID RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3C NR3C1EMA

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