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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CILOSTAZOL
| CILOSTAZOL | BLOOD | ORAL | Cmax 3.25 MICROMOLAR Tmax 2 HOUR PPB 96.5 PERCENT HT 12 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | PHOSPHODIESTERASE III (PDE) | CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A P27815 CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A HOMO SAPIENS ENZYME PHOSPHODIESTERASE PDE_4 PDE_4A | EMA | |||
