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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| THALIDOMIDE
| THALIDOMIDE | ANTINEOPLASTIC | ORAL | Cmax 10.9 MICROMOLAR Tmax 4.3 HOUR VD 61.7 LITER (65 KILOGRAM) PPB 55 PERCENT Cl 8 LITER / HOUR HT 7.29 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | PDB 5AMH (CEREBLON ISOFORM 4 FROM MAGNETOSPIRILLUM GRYPHISWALDENSE IN COMPLEX WITH THALIDOMIDE, TRIGONAL CRYSTAL FORM) LIGAND CODE = EF2 (link to the list of PDB complexes) Download experimental 3D coordinates of EF2 with added hydrogens | PROTEIN CEREBLON Q96SW2 PROTEIN CEREBLON HOMO SAPIENS UNCLASSIFIED | EMA | |||
