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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MODAFINIL
| MODAFINIL ARMODAFINIL | NERVOUS SYSTEM | ORAL | Tmax 3 HOUR VD 58 LITER (65 KILOGRAM) PPB 60 PERCENT Cl 2.6 LITER / HOUR (EQN) HT 15 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | DOPAMINE TRANSPORTER INHIBITOR CHEMBL238 DOPAMINE TRANSPORTER Q01959 SODIUM-DEPENDENT DOPAMINE TRANSPORTER HOMO SAPIENS TRANSPORTER ELECTROCHEMICAL SLC SLC06 | EMA | ||||
