| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METFORMIN
| METFORMIN |
METABOLISM | ORAL | Cmax 13.9 MICROMOLAR Tmax 7 HOUR F 55 PERCENT VD 654 LITER PPB 0 PERCENT Cl 28.8 LITER / HOUR (65 KILOGRAM) HT 17.6 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | Mitochondrial complex I (NADH dehydrogenase) O14561 (ACPM_HUMAN) | EMA | ||||
