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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ATOVAQUONE
| ATOVAQUONE | ANTIPARASITIC | ORAL | Cmax 41.2 MICROMOLAR F 47 PERCENT VD 39 LITER (65 KILOGRAM) PPB 99.9 PERCENT Cl 0.6 LITER / HOUR HT 62.5 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX CORE PROTEIN I, MITOCHONDRIAL (BC1) | Dihydroorotate dehydrogenase (quinone), mitochondrial Q02127 (PYRD_HUMAN) | EMA | |||
