Cheminformatic Tools and Databases for Pharmacology

session 25119 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CIPROFLOXACIN

CIPROFLOXACIN


ATC J01MA02
ATC S01AE03
ATC S02AA15
ATC S03AA07
ATC J01RA10
ATC J01RA12
ATC J01RA11

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
NUCLEIC ACID SYNTHESIS INHIBITORS
QUINOLONES

ORAL INJECTION OPHTHALMIC OTIC

Cmax 16.3 MICROMOLAR (1000 MILLIGRAM)

Tmax 1.5 HOUR

F 70 PERCENT

VD 156 LITER (65 KILOGRAM)

PPB 30 PERCENT

Cl 35 LITER / HOUR

HT 4 HOUR

DNA GYRASE
TOPOISOMERASE 4

PDB 2XCT (THE TWINNED 3.35A STRUCTURE OF S. AUREUS GYRASE COMPLEX WITH CIPROFLOXACIN AND DNA)

LIGAND CODE = CPF (link to the list of PDB complexes)

Download experimental 3D coordinates of CPF with added hydrogens

BACTERIAL DNA GYRASE INHIBITOR CHEMBL2311224 BACTERIAL DNA GYRASE P0AES4 DNA GYRASE SUBUNIT A BACTERIA ENZYME ISOMERASEEMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |