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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TRIENTINE
| TRIENTINE | ANTI-WILSON'S DISEASE (HEPATOLENTICULAR DEGENERATION) AUTOSOMAL INHERITED METABOLIC DEFECT RESULTING IN AN INABILITY TO MAINTAIN A NEARZERO BALANCE OF COPPER | ORAL | SOLUBILITY FREELY SOLUBLE IN WATER | PDB 1DJ6 (COMPLEX OF A Z-DNA HEXAMER, D(CG)3, WITH SYNTHETIC POLYAMINE AT ROOM TEMPERATURE) LIGAND CODE = 104 (link to the list of PDB complexes) Download experimental 3D coordinates of 104 with added hydrogens | COPPER CHELATING AGENT CHEMBL2363057 COPPER | EMA | |||
