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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NIMODIPINE
| NIMODIPINE | CARDIOVASCULAR | ORAL | Tmax 1 HOUR F 13 PERCENT VD 66 LITER PPB 95 PERCENT Cl 54 LITER / HOUR HT 1.5 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | CALCIUM CHANNEL PDB 5KMF (STRUCTURE OF CAVAB IN COMPLEX WITH NIMODIPINE) LIGAND CODE = 6U9 (link to the list of PDB complexes) Download experimental 3D coordinates of 6U9 with added hydrogens | VOLTAGE-GATED L-TYPE CALCIUM CHANNEL BLOCKER CHEMBL2095229 VOLTAGE-GATED L-TYPE CALCIUM CHANNEL O60840 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1F HOMO SAPIENS ION CHANNEL VGC VG CA | EMA | |||
