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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| OXAPROZIN
| OXAPROZIN | MUSCULO-SKELETAL | ORAL | Tmax 3 HOUR F 95 PERCENT VD 10.8 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 0.14 LITER / HOUR (65 KILOGRAM) HT 54.9 HOUR SOLUBILITY INSOLUBLE IN WATER | CYCLOOXYGENASE INHIBITOR CHEMBL2094253 CYCLOOXYGENASE P23219 PROSTAGLANDIN G/H SYNTHASE 1 HOMO SAPIENS ENZYME REDUCTASE | EMA | ||||
