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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ALPROSTADIL
| ALPROSTADIL | CARDIOVASCULAR | INJECTION URETHRAL | Cmax 47 PICOMOLAR Tmax 0.058 HOUR F 98 PERCENT VD 1593 LITER (EQN) PPB 93 PERCENT Cl 6900 LITER / HOUR HT 0.16 HOUR SOLUBILITY SOLUBLE IN WATER | PDB 3WHX (CRYSTAL STRUCTURE OF ANTI-PROSTAGLANDIN E2 FAB FRAGMENT PGE1 COMPLEX) LIGAND CODE = XPG (link to the list of PDB complexes) Download experimental 3D coordinates of XPG with added hydrogens | PROSTANOID EP1 RECEPTOR AGONIST CHEMBL1811 PROSTANOID EP1 RECEPTOR P34995 PROSTAGLANDIN E2 RECEPTOR EP1 SUBTYPE HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL LIPID-LIKE LIGAND RECEPTOR PROSTANOID RECEPTOR | EMA | |||
