| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BUPRENORPHINE
| BUPRENORPHINE |
NERVOUS SYSTEM | INJECTION SUBLINGUAL TRANSDERMAL BUCCAL IMPLANTATION SUBCUTANEOUS | Cmax 10 NANOMOLAR Tmax 1.42 HOUR F 15 PERCENT VD 430 LITER PPB 96 PERCENT Cl 55 LITER / HOUR HT 36.5 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | KAPPA-TYPE OPIOID RECEPTOR MU-TYPE OPIOID RECEPTOR | MU OPIOID RECEPTOR AGONIST CHEMBL233 MU OPIOID RECEPTOR P35372 MU-TYPE OPIOID RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE OPIOID RECEPTOR | EMA | |||
