| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TRAZODONE
| TRAZODONE | NERVOUS SYSTEM | ORAL | Cmax 3.2 MICROMOLAR Tmax 9 HOUR VD 33.8 LITER (65 KILOGRAM) PPB 92 PERCENT Cl 5.4 LITER / HOUR (65 KILOGRAM) HT 10 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | 5-HYDROXYTRYPTAMINE 2A RECEPTOR 5-HYDROXYTRYPTAMINE 2C RECEPTOR ALPHA 1-ADRENERGIC RECEPTOR | SEROTONIN 2A (5-HT2A) RECEPTOR ANTAGONIST CHEMBL224 SEROTONIN 2A (5-HT2A) RECEPTOR P28223 5-HYDROXYTRYPTAMINE RECEPTOR 2A HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR SEROTONIN RECEPTOR | EMA | |||
