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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FLUNISOLIDE
| FLUNISOLIDE | RESPIRATORY SYSTEM | NASAL INHALATION | Cmax 7.6 NANOMOLAR Tmax 0.13 HOUR F 7 PERCENT VD 260 LITER PPB 80 PERCENT (PMID9505980) Cl 125 LITER / HOUR HT 1.5 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | GLUCOCORTICOID RECEPTOR | GLUCOCORTICOID RECEPTOR AGONIST CHEMBL2034 GLUCOCORTICOID RECEPTOR P04150 GLUCOCORTICOID RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3C NR3C1 | EMA | |||
