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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SILODOSIN
| SILODOSIN | GENITO | ORAL | Cmax 124.4 NANOMOLAR Tmax 2.6 HOUR F 32 PERCENT VD 49.5 LITER PPB 97 PERCENT Cl 10 LITER / HOUR HT 13.3 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | ALPHA-1 ADRENERGIC RECEPTOR | ALPHA-1A ADRENERGIC RECEPTOR ANTAGONIST CHEMBL229 ALPHA-1A ADRENERGIC RECEPTOR P35348 ALPHA-1A ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTOR | EMA | |||
