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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ATROPINE
| ATROPINE | NATURAL MOLECULE (link)
METABOLISM | ORAL INTRAMUSCULAR INJECTION INHALATION INTRAVENOUS OPHTHALMIC SUBCUTANEOUS INTRAOSSEOUS ENDOTRACHEAL | Cmax 33.2 NANOMOLAR Tmax 0.05 HOUR VD 214.5 LITER (65 KILOGRAM) PPB 18 PERCENT Cl 29.6 LITER / HOUR (65 KILOGRAM) HT 3 HOUR SOLUBILITY HIGHLY SOLUBLE IN WATER | MUSCARINIC ACETYLCHOLINE RECEPTOR PDB 1TH6 (RUSSELLS VIPER PHOSPHOLIPASE A2) | MUSCARINIC ACETYLCHOLINE RECEPTOR M2 ANTAGONIST CHEMBL211 MUSCARINIC ACETYLCHOLINE RECEPTOR M2 P08172 MUSCARINIC ACETYLCHOLINE RECEPTOR M2 HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ACETYLCHOLINE RECEPTOR | EMA | |||
