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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PHENDIMETRAZINE (has an active metabolite)

PHENDIMETRAZINE

METABOLISM
ANOREXIGENIC
ANTIOBESITY
LOW-POTENCY MONOAMINE-UPTAKE INHIBITOR
PRODRUG FOR THE MONOAMINE-RELEASER PHENMETRAZINE (PM)

ORAL

HT 3.7 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

NORADRENALINE TRANSPORTER
DOPAMINE TRANSPORTER

NOREPINEPHRINE TRANSPORTER INHIBITOR CHEMBL222 NOREPINEPHRINE TRANSPORTER P23975 SODIUM-DEPENDENT NORADRENALINE TRANSPORTER HOMO SAPIENS TRANSPORTER ELECTROCHEMICAL SLC SLC06EMA

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