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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ISOSORBIDE MONONITRATE (is an active metabolite) (has an active metabolite)
| ISOSORBIDE MONONITRATE | CARDIOVASCULAR | ORAL | Cmax 6.5 MICROMOLAR (60 MILLIGRAM) F 100 PERCENT VD 42.2 LITER PPB 0 PERCENT Cl 7 LITER / HOUR HT 5 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | SOLUBLE GUANYLATE CYCLASE ACTIVATOR CHEMBL2111348 SOLUBLE GUANYLATE CYCLASE O75343 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 HOMO SAPIENS ENZYME LYASE GUANYLATE CYCLASE SOLUBLE GUANYLATE CYCLASE | EMA | ||||
