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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PHENYLPROPANOLAMINE DISCONTINUED (is an active metabolite)
| PHENYLPROPANOLAMINE | RESPIRATORY SYSTEM | ORAL | Cmax 1.5 MICROMOLAR (PMID2341583) Tmax 1.47 HOUR VD 206.7 LITER (65 KILOGRAM) Cl 37 LITER / HOUR HT 4.05 HOUR | ALPHA-1 ADRENERGIC RECEPTOR PDB 3U6K (EF-TU (ESCHERICHIA COLI) IN COMPLEX WITH NVP-LDK733) LIGAND CODE = BB8 (link to the list of PDB complexes) Download experimental 3D coordinates of BB8 with added hydrogens | NOREPINEPHRINE TRANSPORTER RELEASING AGENT CHEMBL222 NOREPINEPHRINE TRANSPORTER P23975 SODIUM-DEPENDENT NORADRENALINE TRANSPORTER HOMO SAPIENS TRANSPORTER ELECTROCHEMICAL SLC SLC06 | EMA | |||
