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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NIACIN
| NIACIN |
CARDIOVASCULAR | ORAL | Cmax 146.3 MICROMOLAR Tmax 5 HOUR PPB 20 PERCENT HT 0.56 HOUR SOLUBILITY VERY SOLUBLE IN WATER | PDB 1ICV (THE STRUCTURE OF ESCHERICHIA COLI NITROREDUCTASE COMPLEXED WITH NICOTINIC ACID) LIGAND CODE = NIO (link to the list of PDB complexes) Download experimental 3D coordinates of NIO with added hydrogens | GPCR HCAR2_HUMAN AGONIST Q8TDS4 | EMA | |||
