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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| REVUMENIB
| REVUMENIB | ANTINEOPLASTIC | ORAL | Cmax 5.1 MICROMOLAR Tmax 2 HOUR VD 78 LITER PPB 90 PERCENT Cl 7 LITER / HOUR HT 7.5 HOUR SOLUBILITY SOLUBLE AT PH 1.2 AND 6.8 | MENIN PDB 7UJ4 (INHIBITION OF HUMAN MENIN BY SNDX-5613) LIGAND CODE = OQ4 (link to the list of PDB complexes) Download experimental 3D coordinates of OQ4 with added hydrogens | - more at DrugCentral | EMA | |||
