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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BRENSOCATIB
| BRENSOCATIB | RESPIRATORY | ORAL | Cmax 616 NANOMOLAR Tmax 1.2 HOUR F 80 PERCENT VD 132 LITER PPB 87.2 PERCENT Cl 8.5 LITER / HOUR HT 32 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE AT PH 6.8 IN WATER | DIPEPTIDYL PEPTIDASE 1 (DPP1) | - more at DrugCentral | EMA | |||
