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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was usedPrimary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ENSIFENTRINE

ENSIFENTRINE

RESPIRATORY : PHOSPHODIESTERASE 3 (PDE3) INHIBITOR AND PHOSPHODIESTERASE 4 (PDE4) INHIBITOR INDICATED FOR THE MAINTENANCE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

INHALATION

Tmax 1 HOUR

VD 2700 LITER

PPB 90 PERCENT

HT 11.6 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

PHOSPHODIESTERASE 3 (PDE3)
PHOSPHODIESTERASE 4 (PDE4)

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