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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SULOPENEM (is an active metabolite)
| SULOPENEM ETZADROXIL | ANTIINFECTIVES | - | Cmax 7.6 NANOMOLAR (OR MICROMOLAR UNITS NOT INDICATED) Tmax 2 HOUR F 64 PERCENT VD 92 LITER PPB 11 PERCENT Cl 50.55 LITER / HOUR HT 1.28 HOUR | BETA LACTAMASE | - more at DrugCentral | EMA | |||
