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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ATRASENTAN
| ATRASENTAN | CARDIOVASCULAR | ORAL | Tmax 0.5 HOUR VD 1180 LITER PPB 99 PERCENT Cl 19 LITER / HOUR HT 32.5 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | ENDOTHELIN RECEPTOR TYPE A ETA | - more at DrugCentral | EMA | |||
