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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was usedPrimary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M AZACITIDINE (is an active metabolite)

AZACITIDINE


ATC L01BC07

ANTINEOPLASTIC
ANTIMETABOLITES
FAB MYELODYSPLASTIC SYNDROME
CYTOTOXIC
NUCLEOSIDE ANALOG OF CYTIDINE
HYPOMETHYLATION OF DNA AND RNA AFTER PHOSPHORYLATION BY KINASE UCK2

- DNA
DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 DNMT1

DNA (cytosine-5)-methyltransferase 1 UNIPROT P26358 DNMT1 -- DNA (cytosine-5)-methyltransferase 3A UNIPROT Q9Y6K1 DNMT3A

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