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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MOBOCERTINIB (has an active metabolite)
| MOBOCERTINIB | ANTINEOPLASTIC | ORAL | Tmax 4 HOUR F 37 PERCENT VD 3509 LITER PPB 99.3 PERCENT Cl 138 LITER / HOUR HT 18 HOUR SOLUBILITY 17 MILLIGRAM PER MILLILITER AT PH 6.8 | EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) (MUTATED) HER2 HER4 BLK | More at DrugCentral | EMA | |||
