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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BELUMOSUDIL
| BELUMOSUDIL | ANTINEOPLASTIC | ORAL | Cmax 5.2 MICROMOLAR Tmax 1.9 HOUR F 64 PERCENT VD 184 LITER PPB 99.9 PERCENT Cl 9.83 LITER / HOUR HT 19 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | ROCK2 KINASE | More at DrugCentral | EMA | |||
