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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| VOXELOTOR
| VOXELOTOR | BLOOD | ORAL | Cmax 11.3 MILLIMOLAR Tmax 2 HOUR VD 338 LITER PPB 99.8 PERCENT Cl 6.7 LITER / HOUR HT 35.5 HOUR SOLUBILITY INSOLUBLE IN WATER (APPROXIMATELY 0.03 MILLIGRAM PER MILLILITER) | HEMOGLOBIN (HBS) | hemoglobin subunit alpha (transporter) INHIBITOR P69905 (HBA_HUMAN) | EMA | |||
