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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BEMPEDOIC ACID
| BEMPEDOIC ACID | CARDIOVASCULAR | ORAL | Cmax 59.8 MICROMOLAR Tmax 3.5 HOUR VD 18 LITER PPB 99.3 PERCENT Cl 0.68 LITER / HOUR HT 21 HOUR SOLUBILITY INSOLUBLE IN WATER | ADENOSINE TRIPHOSPHATE-CITRATE LYASE (ACL) | enzyme ATP-citrate synthase inhibitor P53396 ACLY_HUMAN | EMA | |||
