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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DACOMITINIB
| DACOMITINIB | ANTINEOPLASTIC | ORAL | Cmax 230 NANOMOLAR Tmax 6 HOUR F 80 PERCENT VD 1889 LITER PPB 98 PERCENT Cl 24.9 LITER / HOUR HT 70 HOUR | EGFR KINASE | Epidermal growth factor receptor P00533 | EMA | |||
