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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PRUCALOPRIDE
| PRUCALOPRIDE | METABOLISM | ORAL | Cmax 19 NANOMOLAR Tmax 2.5 HOUR F 90 PERCENT VD 567 LITER PPB 30 PERCENT Cl 19 LITER / HOUR HT 24 HOUR SOLUBILITY HIGHLY SOLUBLE IN ACIDIC AQUEOUS MEDIA | SEROTONIN-4 (5-HT4) | 5-hydroxytryptamine receptor 4 5HT4R_HUMAN Q13639 5-hydroxytryptamine receptor 3A 5HT3A_HUMAN P46098 D(4) dopamine receptor DRD4_HUMAN P21917 | EMA | |||
