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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CRISABOROLE
| CRISABOROLE | DERMATOLOGICALS | TOPICAL | Cmax 506 NANOMOLAR PPB 97 PERCENT SOLUBILITY INSOLUBLE IN WATER | PHOSPHODIESTERASE 4 | ENZYME PDE4A_HUMAN INHIBITOR P27815 PDE4B_HUMAN INHIBITOR Q07343 PDE4C_HUMAN INHIBITOR Q08493 PDE4D_HUMAN INHIBITOR Q08499 | EMA | |||
