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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METHYLENE BLUE (has an active metabolite)
| METHYLENE BLUE | TREATMENT OF METHEMOGLOBINEMIA | INTRAVENOUS | Cmax 10.3 MICROMOLAR VD 255 LITER PPB 94 PERCENT HT 24 HOUR SOLUBILITY SOLUBLE IN WATER | NADPH REDUCTASE PDB 5DLP (ACETYCHOLINESTERASE METHYLENE BLUE NO PEG) LIGAND CODE = MBT (link to the list of PDB complexes) Download experimental 3D coordinates of MBT with added hydrogens | IRON | EMA | |||
