Cheminformatic Tools and Databases for Pharmacology

session 89044 - Total of 1 hits - Display   hits per page:

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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DESOXYCORTICOSTERONE (is an active metabolite)

DESOXYCORTICOSTERONE


ATC H02AA03

HORMONES
ADRENOCORTICAL STEROID
PRECURSOR OF ALDOSTERONE
SUBSTRATE OF ALDOSTERONE SYNTHASE (CYTOCHROME P450 CYP11B2)

- ALDOSTERONE SYNTHASE

PDB 2AA7 (MINERALOCORTICOID RECEPTOR WITH BOUND DEOXYCORTICOSTERONE)

LIGAND CODE = 1CA (link to the list of PDB complexes)

Download experimental 3D coordinates of 1CA with added hydrogens

MINERALOCORTICOID RECEPTOR AGONIST CHEMBL1994 MINERALOCORTICOID RECEPTOR P08235 MINERALOCORTICOID RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3C NR3C2EMA

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