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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ISAVUCONAZONIUM (has an active metabolite)
| ISAVUCONAZONIUM | ANTIINFECTIVES | ORAL INTRAVENOUS | LANOSTEROL 14 ALPHA-DEMETHYLASE (CYTOCHROME P450 P-45014DM PMID26598096) | LANOSTEROL 14-ALPHA DEMETHYLASE INHIBITOR CHEMBL3390825 LANOSTEROL 14-ALPHA DEMETHYLASE A0A0A1P6P0 MUCORALES ENZYME CYTOCHROME P450 CYP_51 CYP_51A CYP_51A1 | EMA | ||||
