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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BREXPIPRAZOLE
| BREXPIPRAZOLE | NERVOUS SYSTEM | ORAL | Tmax 4 HOUR F 95 PERCENT VD 101.4 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 1.28 LITER / HOUR (65 KILOGRAM) HT 91 HOUR | 5-HT1A RECEPTORS DOPAMINE D2 RECEPTOR 5-HT2A RECEPTOR | SEROTONIN 1A (5-HT1A) RECEPTOR PARTIAL AGONIST CHEMBL214 SEROTONIN 1A (5-HT1A) RECEPTOR P08908 5-HYDROXYTRYPTAMINE RECEPTOR 1A HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR SEROTONIN RECEPTOR | EMA | |||
