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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LENVATINIB
| LENVATINIB | ANTINEOPLASTIC | ORAL | Tmax 2.5 HOUR F 85 PERCENT VD 82 LITER PPB 98.5 PERCENT HT 28 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | VEGFR RECEPTORS PDB 3WZD (KDR IN COMPLEX WITH LIGAND LENVATINIB) LIGAND CODE = LEV (link to the list of PDB complexes) Download experimental 3D coordinates of LEV with added hydrogens | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET P07949 PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET HOMO SAPIENS ENZYME KINASE PROTEIN KINASE TK RET | EMA | |||
