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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| EDOXABAN
| EDOXABAN | CARDIOVASCULAR | ORAL | Tmax 1.5 HOUR F 62 PERCENT VD 107 LITER PPB 55 PERCENT Cl 22 LITER / HOUR HT 12 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE AT PH 6-7 | FACTOR XA | COAGULATION FACTOR X INHIBITOR CHEMBL244 COAGULATION FACTOR X P00742 COAGULATION FACTOR X HOMO SAPIENS ENZYME PROTEASE SERINE PAS S1A | EMA | |||
