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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ELIGLUSTAT
| ELIGLUSTAT | METABOLISM | ORAL | Cmax 339 NANOMOLAR Tmax 3 HOUR VD 835 LITER PPB 79.5 PERCENT Cl 88 LITER / HOUR HT 8.9 HOUR | GLUCOSYLCERAMIDE SYNTHASE | CERAMIDE GLUCOSYLTRANSFERASE INHIBITOR CHEMBL2063 CERAMIDE GLUCOSYLTRANSFERASE Q16739 CERAMIDE GLUCOSYLTRANSFERASE HOMO SAPIENS ENZYME TRANSFERASE | EMA | |||
