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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BENZHYDROCODONE (has an active metabolite)
| BENZHYDROCODONE |
NERVOUS SYSTEM | ORAL | MU-TYPE OPIOID RECEPTOR | More at DrugCentral | EMA | ||||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| HYDROCODONE (is an active metabolite) (has an active metabolite)
| HYDROCODONE | RESPIRATORY SYSTEM | ORAL | Cmax 76.2 NANOMOLAR Tmax 3.4 HOUR HT 16 HOUR | DELTA-TYPE OPIOID RECEPTOR KAPPA-TYPE OPIOID RECEPTOR MU-TYPE OPIOID RECEPTOR | OPIOID RECEPTORS MU/KAPPA/DELTA AGONIST CHEMBL2095181 OPIOID RECEPTORS MU/KAPPA/DELTA P35372 MU-TYPE OPIOID RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE OPIOID RECEPTOR | EMA | |||
| 3 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| HYDROMORPHONE (is an active metabolite)
| HYDROMORPHONE |
NERVOUS SYSTEM | INJECTION ORAL | Cmax 20 NANOMOLAR Tmax 0.73 HOUR VD 302.9 LITER PPB 13 PERCENT Cl 117.6 LITER / HOUR HT 2.3 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | MU-TYPE OPIOID RECEPTOR | MU OPIOID RECEPTOR AGONIST CHEMBL233 MU OPIOID RECEPTOR P35372 MU-TYPE OPIOID RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE OPIOID RECEPTOR | EMA | |||
