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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DIMETHYL FUMARATE (has an active metabolite)
| DIMETHYL FUMARATE | NERVOUS SYSTEM | ORAL | SOLUBILITY HIGHLY SOLUBLE IN WATER | NICOTINIC ACID RECEPTOR (NIACR) PDB 6LRZ (CRYSTAL STRUCTURE OF KEAP1 IN COMPLEX WITH DIMETHYL FUMARATE (DMF)) LIGAND CODE = EOU (link to the list of PDB complexes) Download experimental 3D coordinates of EOU with added hydrogens | KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 INHIBITOR CHEMBL2069156 KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 Q14145 KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 HOMO SAPIENS UNCLASSIFIED | EMA | |||
