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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| POMALIDOMIDE
| POMALIDOMIDE | ANTINEOPLASTIC | ORAL | Cmax 0.27 MICROMOLAR VD 100 LITER PPB 28 PERCENT Cl 8 LITER / HOUR HT 9.5 HOUR SOLUBILITY LOW SOLUBILITY IN WATER | PDB 4CI3 (STRUCTURE OF THE DDB1-CRBN E3 UBIQUITIN LIGASE BOUND TO POMALIDOMIDE) LIGAND CODE = Y70 (link to the list of PDB complexes) Download experimental 3D coordinates of Y70 with added hydrogens | PROTEIN CEREBLON Q96SW2 PROTEIN CEREBLON HOMO SAPIENS UNCLASSIFIED | EMA | |||
