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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| OMACETAXINE MEPESUCCINATE
| OMACETAXINE MEPESUCCINATE | ANTINEOPLASTIC | SUBCUTANEOUS | VD 141 LITER PPB 50 PERCENT Cl 16.3 LITER / HOUR (EQN) HT 6 HOUR | RIBOSOME PDB OBSOLETE (- 4UL7 CRYSTAL STRUCTURE OF HOMOHARRINGTONINE BOUND TO THE YEAST 80S RIBOSOME) LIGAND CODE = HMT (link to the list of PDB complexes) Download experimental 3D coordinates of HMT with added hydrogens | PROTEIN SYNTHESIS INHIBITOR | EMA | |||
