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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DIENOGEST
| DIENOGEST |
GENITO | ORAL | Cmax 294.8 NANOMOLAR (3 MILLIGRAM) F 91 PERCENT VD 46 LITER (85 MICROGRAM IV) PPB 90 PERCENT Cl 2.9 LITER / HOUR (EQN) HT 11 HOUR | PROGESTERONE RECEPTOR | PROGESTERONE RECEPTOR P06401 PROGESTERONE RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3C NR3C3 | EMA | |||
