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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| RALTEGRAVIR
| RALTEGRAVIR | ANTIINFECTIVES | ORAL | Tmax 3 HOUR F 60 PERCENT PPB 83 PERCENT HT 9 HOUR SOLUBILITY SOLUBLE IN WATER | INTEGRASE PDB 4MDB (STRUCTURE OF MOS1 TRANSPOSASE CATALYTIC DOMAIN AND RALTEGRAVIR WITH MG) LIGAND CODE = RLT (link to the list of PDB complexes) Download experimental 3D coordinates of RLT with added hydrogens | GAG-POL POLYPROTEIN P03367 GAG-POL POLYPROTEIN HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 GROUP M SUBTYPE B (ISOLATE BRU/LAI) UNCLASSIFIED | EMA | |||
